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Glutamine increases the activity of glutamine synthase (GLS) and glutamate dehydrogenase (GDH) by regulating the mTOR/S6 and MAPK pathways, thereby promoting tumor cell proliferation [282]

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Patients taking warfarin or other coumarin anticoagulants should have their INR monitored more frequently when starting or adjusting Ozempic, as changes in diet, weight, or gastrointestinal function may indirectly affect anticoagulation control