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J Med Chem 58:73707380 Lee TS, Park EJ, Choi M, Oh HS, An Y, Kim T, Kim TH, Shin BS, Shin S (2023) Novel LC-MS/MS analysis of the GLP-1 analog semaglutide with its application to pharmacokinetics and brain distribution studies in rats

Compared to alternative antidiabetic regimens, GLP-1 analogs are particularly helpful in mediating weight loss in obese, diabetic patients on antidepressants, particularly in patients on selective serotonin reuptake inhibitors

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[6] [5] The mechanism of action centres on several key physiological effects