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Superoxide anions may directly react with NO, thereby stimulating the production of the NO/superoxide anion reaction product peroxynitrite (ONOO ), which in turn has been shown to uncouple the endothelial nitric oxide synthase (eNOS), thereby causing an anti-atherosclerotic NO-producing enzyme to become a ROS-producing enzyme, thus accelerating the atherosclerotic process

Apart from hydrolases, two individual degradative gene clusters each for PA and PCA metabolism were detected (Additional file 8: Table S3, Fig

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A mathematical model of the methionine cycle