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Psychiatry 16 , 19 (2017)

Intranasal administration is particularly studied for its ability to bypass the blood-brain barrier via retrograde axonal transport

63, 64 Interestingly, the presence of proinflammatory cytokines and activated neuroglia have been reported in the autism cerebellum among other regions, 9 suggesting that activated neuroglia produce excess NO and may contribute to the peroxynitrite formation and increased 3-NT protein damage observed in the present study