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NaBPC157 (10 g or 10 ng/kg b.w., i.p.) or saline (5.0 ml/kg b.w., i.p.) was applied either 1 hour before or 1 hour after both carotid arteries were ligated for 3 or 6 hours in rats

In the case of cigarette smoking, studies initially suggested that smoking reduced the risk of AD, but subsequent prospective studies have shown an increased risk or no association (Mayeux and Stern 2012)

Response: We thank commenters for their concerns regarding the impact of the proposed update to the Overall Hospital Quality Star Rating methodology for small and rural hospitals

Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans. Sci Transl Med