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Unlike traditional weight management strategies, GLP-1-based therapies target the neuroendocrine regulation of hunger and satiety, making them highly effective in obesity treatment
It is highly expressed in the hypothalamus, where it plays a crucial role in the regulation of protein trafficking and recycling, which affect secretory granule biogenesis ( MAGEL2 cause Schaaf-Yang syndrome (MIM: 615547), which is characterized by delayed psychomotor development, frequent intellectual disability, hypotonia, feeding difficulties, and various dysmorphic facial features
And it can sometimes cause people to try to get Vyvanse illegally
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