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Indications Reconstitution of lyophilized powders for injection (e.g., hormones, peptides) Dilution of injectable medications Used in intramuscular, subcutaneous, or intravenous routes as directed by medication instructions Dosage and Administration Dosage determined by the medication being reconstituted or diluted For parenteral use only Use a sterile needle and syringe when accessing the vial After first use, discard unused portion after 28 days Do not use if solution is discolored, cloudy, or contains particulates Contraindications Neonates (newborns), due to risk of gasping syndrome caused by benzyl alcohol Known hypersensitivity to benzyl alcohol or any component of the solution Precautions Use with caution in pregnant or breastfeeding women Caution in patients with hepatic or renal impairment Use only with medications compatible with bacteriostatic water Not for use as a standalone injection without a compatible solute Possible Side Effects Local injection site irritation or inflammation Allergic reactions: rash, itching, facial swelling, trouble breathing (rare) Benzyl alcohol toxicity in sensitive populations (especially neonates) Drug Interactions Bacteriostatic Water itself has no pharmacologic interaction
Hypokalemia (low potassium) In rare cases, excessive B12 therapy can affect potassium levels.
[DOI] [PubMed] [Google Scholar] Laffont C
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