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The multidistrict litigation (MDL) against pharmaceutical companies Novo Nordisk and Eli Lilly, involving GLP-1 drugs like Ozempic, Wegovy, Trulicity, and Mounjaro, continues to develop as plaintiffs allege these medications have caused significant gastrointestinal injuries

Extending the short-term GLP-1 Bridge program is good news for eligible Medicare beneficiaries because it provides the certainty of obesity drug coverage at a $50 copay for a longer duration, but federal spending will also rise by some unknown amount since CMS hasnt disclosed the projected cost

In fact, POMC and AgRP neurons modulate autonomic nerve activity in various tissues, including fat depots 34 , and these neurons can regulate fasting-induced fall in leptin levels, independently of changes in fat mass 35