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Recommended Treatment Schedules While we personalise recommendations for each client, typical B12 injection schedules include: Initial phase : Weekly injections for 4-6 weeks to replenish B12 stores Maintenance phase : Monthly injections to sustain optimal levels Situational support : Additional injections during periods of increased stress, illness, or intense physical activity Your practitioner will work with you to determine the ideal frequency based on your response to treatment and ongoing needs