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The phase 2 trial published in The New England Journal of Medicine in 2023 enrolled adults with obesity without type 2 diabetes and demonstrated dose-dependent weight loss of up to 24.2% of body weight at the highest dose over 48 weeks results that attracted considerable scientific and media attention

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NOT Cost-Effective For Insurance-covered patients: Don't pay $300/month cash when insurance covers standard GLP-1s at $25-$100 copays