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A related formulation, Wegovy (higher-dose semaglutide at 2.4 mg), has received MHRA approval specifically for weight management in individuals with obesity or overweight with comorbidities, but this remains distinct from bodybuilding applications

In the current study, Atieh and colleagues examined the impact of semaglutide on neurocognitive function and any mediation from improved adiposity and inflammatory markers

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While some users report enhanced libido due to improved health and weight loss, others may experience a decreased sex drive due to side effects, hormonal changes, or lower energy from reduced calorie intake