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De Franceschi, N., Hamidi, H., Alanko, J., Sahgal, P
5 NAC combined with biomaterials for bone tissue engineering Bone tissue, a highly organized natural composite material, integrates organic and inorganic substances with various cell types within the extracellular matrix (ECM) scaffold ( Polymethyl methacrylate (PMMA) bone cement is extensively used in orthopedic surgery, but the high elastic modulus and low biocompatibility have limited further advancements (Zhu et al., 2020
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