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Many apparent stalls are simply someone still early in the ladder expecting a maintenance-level effect
About 12 percent of Americans have tried a GLP-1, RAND reports
Therefore, we found that the enhanced insulinotropic effect of exendin-phe1 in vitro is recapitulated in a mouse model of T2D, suggesting that GLP-1R trafficking plays a role in determining the responses to therapeutic GLP-1R agonists in vivo
Between July 2023 - when Intuitive first mentioned weight loss drugs - and October 2023, medical device companies that were deemed GLP-1 losers sold off aggressively (e.g., diabetes medical devices, sleep apnea devices, bariatric surgery), while the GLP-1 companies themselves (Eli Lilly and Novo Nordisk) increased in value much more than the broader market
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