However, the goal of the study was to assess the negative impact of chronic alcohol exposure in a rodent model that translationally mimics AUD, which is not captured in the Wistar rats using standard non-dependent 2BC procedures
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Interestingly, RYGB controls 5-HT 2A receptor availability in the ventral striatum in rats [112], suggesting that GLP-1R agonists and bariatric surgery may both target the midbrain serotonergic system to exert their inhibitory effects on energy balance
When activated, GLP-1 receptors reduce harmful inflammation, lower blood pressure, improve how efficiently your heart pumps, and help your kidneys manage fluid and sodium better