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The primary and secondary endpoints of the study were safety and pharmacokinetic parameters, and fasting serum glucose was measured pre-dose and post-dose in study participants, all of whom had glucose and glycated hemoglobin (HbA1c) levels within the normal reference range for the laboratory

(A) The structure of hepatocyte growth factor (HGF) includes a -chain (69 kDa) of four Kringle domains and a -chain (43 kDa) consisting of a serine proteinase homology (SPH) domain linked by disulfide bonds

Given that an average rat weighing 200 g drinks approximately 4050 ml/day [120], it would consume 3645 mg of NAC daily, corresponding to 180225 mg/kg/day

Suggested Dosage Most clinical studies use dosages ranging from 500 mg to 2,000 mg per day