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It is not known whether GPR 119 and/or 120 are located to the luminal (brush border) membrane, which is primarily involved in sensing NEFA in chymus, or to the baso-lateral membrane, where they would be exposed to interstitial fluid more similar in composition to plasma (Fig

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2024;29(11):377 Kanamori M, Nakatsukasa H, Okada M, Lu Q, Yoshimura A

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