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The proportion of participants with resistant hypertension at baseline (n=167) that reached BP targets at week 68 was 42.0% and 29.3% for CagriSema and placebo, respectively (odds ratio, 1.7 [95% CI, 0.74.4])

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Studies examining the timing of combined administration have consistently shown that simultaneous or near-simultaneous administration produces maximal synergy, with the synergistic component declining as the interval between administrations increases beyond 15-30 minutes