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doi: 10.1016/j.iac.2016.08.003 210 FrazierWBhardwajN

Metabolic Liver Disease (Fatty Liver / MASLD) Silymarin has been extensively studied for metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as non-alcoholic fatty liver disease or NAFLD) and its more severe form, MASH (formerly NASH) [1][23][24]

FDAs May 2026 TB-500 assessment stated that it found no human data for products containing the defined TB-500 substances and found insufficient nonclinical evidence to support wound-healing effectiveness