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By contrast, lack of such correlations in brains of patients with SZ point to a disturbance of redox coupling mechanisms in the AODS, possibly resulting from a decreased level of glutathione (GSH) as well as age-related decreases of oxidized GSH and GSH reductase activities

MCS is referred to in studies by several different terms, and there is controversy or confusion around the diagnosis due to a lack of understanding of the underlying causes

Treatment with 2-mercaptoethanol increased the overall GSH concentration of uninfected cells (Fig 2B, compare bars 1 and 3

To test this data interpretation, we analyzed the GSSG-dependent oxidation of reduced fusion constructs between roGFP2 WT and wild-type PfGrx (PfGrx WT ), the dithiol mutant PfGrx C88S , or the monothiol mutant PfGrx C32S/C88S (Fig