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Description

This should be considered a meaningful safety concern

4.1 Diagnosis There are no standard diagnostic criteria for SJS/TEN, though the presence of macular targetoid lesions, involvement of two mucous membranes, recent drug exposure, and corresponding histopathology are all suggestive

It is composed of three amino acids: glycine, cysteine, and glutamic acid

The representative transcription factors mediated by HDACs include p53, signal transduction and activation of transcription 1 (STAT1), STAT3, GATA-binding factors (e.g