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Where it comes up most often: Where it is not firmly established: That distinction matters

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(More information) Low maternal vitamin B 12 status has been associated with an increased risk of neural tube defects (NTD), but it is not known whether vitamin B 12 supplementation could help reduce the risk of NTD

Comment: Many commentors expressed support for the CMS proposal to modify the language at 414.1455(b)(3)(ii) and (b)(3)(vi) to the same timing requirements as that of MIPS Targeted Reviews specified at 414.1385(a)(2) and (a)(5)