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With further research, it is expected to transform from a research tool into a clinical drug, filling the niche in targeted metabolic therapy, especially in the combined intervention of obesity and type 2 diabetes, where it holds unique application potential

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This review has systematically summarized evidence suggesting that L-carnitine exerts multi-targeted actions against MASLD pathogenesis by promoting lipid metabolism, improving insulin sensitivity, stabilizing hepatocyte function, and inhibiting inflammatory and fibrotic signaling pathways