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For example, data indicate that slightly more than half of patients with T2DM meet the general hemoglobin A1C goal of less than 7%, and suboptimal glycemic control continues to contribute to the development of complications like cardiovascular disease and microvascular complications

According to several large recent clinical trials and thorough examination of GLP-1R expression in various pancreatic pathologic conditions, these kinds of concerns in humans have decreased but have not clearly vanished [14,15,16,17]

GLP-1 Receptors Glucagon-like peptide (GLP-1) receptor agonists are used to treat diabetes by activating GLP-1 receptors in the pancreas, which leads to enhanced insulin release and reduced glucagon release responses that are glucose-dependent, with a consequent low risk for hypoglycemia

Hill-Briggs F, Adler NE, Berkowitz SA et al (2021) Social determinants of health and diabetes: a scientific review