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Temporary subsidies imposed by the Centers for Medicare & Medicaid Services (CMS) through the agencys new premium stabilization program will increase spending by $5 billion in 2025

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This three-pathway mechanism is one reason retatrutide has gained significant attention in obesity medicine and clinical research, and why many are already referring to it as the next generation of weight-loss medications. Clinical trials for retatrutide began several years ago, with Phase 2 data generating significant interest due to the amount of weight loss observed in study participants

Overall Estimated Burden on Hospitals Due to HPT Requirements To analyze the costs of the requirements, we used an updated baseline that assumes the existing requirements (those adopted in the CY 2020 HPT final rule, the CY 2022 OPPS/ASC final rule with comment period and the CY 2024 OPPS/ASC final rule with comment period and still codified at 45 CFR part 180) remain in place over the time horizon of this RIA