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These taxa form a pathogenic synergistic network: Prevotella provides metabolic substrates through carbohydrate degradation, Fusobacterium enhances biofilm structural stability to facilitate persistent colonization, and Porphyromonas secretes virulence factors that damage periodontal tissues and suppress host immunity

These results demonstrated that PTK hydrogel as a cell-free cartilage scaffold could induce the directional migration of BMSCs for further chondrocyte differentiation and cartilage regeneration

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