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In the four-year XENDOS trial, people taking it lost an average of 5.8 kg versus 3.0 kg on placebo, and had a lower risk of developing type 2 diabetes

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Of course, older adults, people over age 50 in particular, tend to have the lowest B12 levels, though vegetarians and those who have undergone gastric bypass surgery are also at a higher risk

To further screen overlapped DEGs for osteogenic proliferation and differentiation under semaglutide treatment, we used osteoblast proliferation, osteoblast differentiation and osteoblast development as the main biological processes to screen overlapped DEGs as indicated by the Venn diagram (Figure 4B) and obtained the key gene LRP5