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[19] [20] Additionally, excess weight may contribute to mobility limitations and could potentially increase fall risk and worsen heat sensitivitya common trigger for temporary symptom worsening in MS

In practice, GI side effects especially constipation are among the most common reasons patients struggle to stay on these medications

While these effects are highly beneficial for managing Type 2 diabetes and obesity, the fact that the medication interacts with the bodys complex hormonal (endocrine) system is why the thyroid has become a topic of discussion

Topline data from REDEFINE 1 found CagriSema, a fixed-dose combination of cagrilintide 2.4 mg and semaglutide 2.4 mg, achieved superior weight loss versus placebo in adults with obesity or overweight