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Safety Considerations and Side Effects Like all medications, GLP-1 drugs have potential side effects: Common side effects include: Nausea, vomiting, diarrhea (usually improving over time) Constipation Stomach pain or indigestion Injection site reactions (mild redness or itching) Less common but more serious concerns include: Pancreatitis (inflammation of the pancreas) Kidney problems Gastroparesis (stomach paralysis) in rare cases Joint and bone issues like arthritis and tendinitis Researchers found no established link between GLP-1 medications and pancreatitis, pancreatic cancer, or thyroid cancer in large studies with years of follow-up

Here are the caveats: The most serious potential impact associated with GLP-1 agonists includes worsening and progression of diabetic retinopathy

Fresh from the biotech pipeline: fewer approvals, but biologics gain share

This remains its primary use, but it became increasingly common for doctors to prescribe it to obese patients off-label as a treatment to control weight