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Funding This investigation was supported by the National Natural Science Foundation of China (grant number: 82200304), the Natural Science Foundation of Heilongjiang Province (grant number: PL2025H107), Heilongjiang Provincial Universities Outstanding Young Faculty Basic Research Support Program (grant number: YQJH2025132), China Heart House-Chinese Cardiovascular Association-2024 TCM fund (grant number: 2024-CCA-TCM-030)

2023) and euthanized by cervical dislocation

On a U-100 insulin syringe, researchers typically draw 5 to 10 units per administration, which equals 2mg to 4mg of total blend