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Injectable drugs, such as semaglutide, liraglutide, and diraglutide, involve GLP-1 receptor agonists, which simulate the actions of natural GLP-1 by binding to and stimulating its receptors

In another systematic review that included individuals with T2D from 38 phase III or IV placebo-controlled randomized controlled trials with GLP-1RAbased therapy (16), nausea was reported in 19.3% of participants with active treatment versus 6.5% with placebo, and vomiting was reported in 7.6% of participants versus 2% with placebo

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