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Dasatinib has shown antifibrotic effects in keloid fibroblasts and xenotransplant keloid tissue in mice through the selective clearance of senescent cells and modulation of SASP, implying that dasatinib can be possibly used for senolytic treatment of keloids 15

10.1155/2019/7167525 [DOI] [PMC free article] [PubMed] [Google Scholar] Kuang H., Zhao D., Tian Z., Liu Z., Dai S., Zheng Y., et al

One expected outcome of this effect is the GRK2-mediated modulation of -arrestin-mediated desensitization and thus of the canonical GLP-1R-dependent signaling pathways known to modulate insulin release

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