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The AEs in REAC files are encoded by the preferred terms (PTs) in the Medical Dictionary for Regulatory Activities (MedDRA) terminology, which is comprised of 27 system organ classes (SOCs) ( Demographics (gender, age), reporting characteristics (reporting region, year, occupation of reporters), and indications of reports of GLP-1 RA-associated gastrointestinal toxicities were analyzed

These ROS molecules play a crucial role in augmenting the platelet activation response through various signaling pathways, including isoprostane formation, Ca 2+ mobilization, and NO inactivation

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