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For diabetes management (marketed as Victoza), the maximum dose is lower at 1.8 mg daily

The SUSTAIN clinical trial programme has documented Semaglutides superior glycaemic and weight-reducing efficacy relative to placebo, sitagliptin, exenatide extended-release, insulin glargine, and dulaglutide establishing Semaglutide as the highest-efficacy selective GLP-1R agonist in comparative clinical pharmacology and providing the translational reference dataset for pre-clinical mechanistic research into the molecular basis of its superior outcomes

Research suggests Mounjaro may lead to greater average weight loss 25% after one year compared to 16% with Wegovy

Weeks 5-8: For many users, this is when adaptation begins