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By delaying gastric emptying, semaglutide may alter the rate and extent of absorption of orally administered medications, particularly those requiring rapid absorption for optimal effect or those with a narrow therapeutic window

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Mutagenicity tests on microorganisms --------------------------------------------------------------------------------------------------------- Organism/strain Dose Type of test Metabolic Result Reference activation --------------------------------------------------------------------------------------------------------- Bacillus subtilis H17 rec + 0.02 ml of plate none - Shirasu et al