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Records should include detailed description of the side effect, date and time of onset, severity assessment, relationship to IGF1 LR3 use, interventions tried and their effectiveness, communication with research supervisors or medical personnel, any protocol changes made, and outcome (resolution, persistence, or progression of symptoms)

In animal models, researchers measure parameters such as circulating free fatty acids, respiratory exchange ratios, and adipose tissue gene expression to characterize shifts in substrate utilization

The treatment is quick and involves a slight discomfort, often described as a slight pinch at the injection site