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Description

As shown in Figure S7 , the niclosamide UV/Vis spectra from 25uM to 300uM all show the characteristic double peak profile at this pH of 9.3, with max maxima at 333nm and 377nm, although the maximum in aqueous pH 9.3 buffer was closer to 335nm

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The enzymatic activity of prolyl 4-hydroxylase subunit alpha 1 (P4HA1), a procollagen-proline, 2-oxoglutarate 4-dioxygenase, is crucial for collagen polypeptide chain folding into stable triple-helical molecules and consequently for ECM deposition [23]