Potential Risks and Unknowns Because TB500 influences angiogenesis and cell proliferation , some researchers have raised theoretical concerns about: Promoting unwanted cell growth (e.g., in precancerous tissues) Interfering with natural inflammatory processes during healing Suppressing immune responses with long-term or high-dose use There is no conclusive evidence showing carcinogenicity, but as with any peptide that affects growth and regeneration, caution is warranted especially if theres a history of tumors or systemic disease
Doctors commonly choose to give shots in the deltoid (shoulder) muscle, though the gluteus maximus (buttocks) muscle is sometimes used
doi: 10.1097/FTD.0b013e3181817428 Summary Keywords busulfan, pharmacokinetics, pediatric, therapeutic drug monitoring, hematopoietic cell transplantation Citation Shukla P, Goswami S, Keizer RJ, Winger BA, Kharbanda S, Dvorak CC and Long-Boyle J (2020) Assessment of a Model-Informed Precision Dosing Platform Use in Routine Clinical Care for Personalized Busulfan Therapy in the Pediatric Hematopoietic Cell Transplantation (HCT) Population
This target does not change during a stall, in fact, meeting it consistently becomes even more important during a stall because muscle preservation is the primary lever you have for maintaining metabolic rate
