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In addition, the authors noted that the results should not be generalized to other GLP-1RA with different pharmacokinetic profiles ( Cardiovascular Outcomes DPP-4 Inhibitors Five trials enrolling almost 50,000 patients have evaluated the cardiovascular safety of DPP-4 inhibitors

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It addresses the pitfalls above through two core strategies: 1) a highly personalized low and slow titration protocol aimed at maximizing tolerability and finding the right dose for each individual, in combination with 2) deep lifestyle integration using behavioral science focused on ensuring patients build healthy habits alongside the medication