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FM typically occurs in middle-aged women at a ratio of 3:1, although it can affect both sexes at any age (Brum et al

Weight loss results vary depending on dosage, genetics, adherence, lifestyle factors, and more

In relation to clinical trials, the most relevant ones were collected, emphasizing those with phase 2, except for some phase 1 trials with a very novel mechanism of action

The clinical presentation of hypothyroidism reflects the consequences of a slowed metabolic rate: fatigue, weight gain, cold intolerance, constipation, dry skin, bradycardia, and, in some patients, depression