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Specifically, differences between IF1-P and IF2-P GI symptoms at baseline were compared using a Fishers Exact test, whereas pre-post values were compared with McNemars test

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### What the Clinical Data Shows Analysis of STEP trial body composition data published in *Diabetes, Obesity and Metabolism* (2023) revealed: - Approximately **6075% of total weight lost on semaglutide was fat mass** - The remaining 2540% included water, glycogen, and some lean tissue - Lean mass loss was proportional to what is expected with any significant weight reduction ### How Bodybuilders Can Optimize Muscle Preservation on GLP-1 Peptides The key insight for the bodybuilding community is that lean mass loss on GLP-1 peptides is **highly modifiable** through training and nutrition

And in the wild cases of Wegovy and Lilly's Mounjaro, the more superficial and the more knee jerk they were, the more money they saved," he said