Since PBMs emerged decades ago to help plans manage prescriptions, rebates and discounts, they evolved into powerful intermediaries that influence almost every aspect of the drug benefit
In many cases, a provider may consider changing the route or protocol if clinically appropriate
About 12,000 people starting GLP-1 drugs were compared against roughly 15,200 starting SGLT-2 inhibitors, and a separate group of about 12,000 GLP-1 starters was compared against 11,233 starting DPP-4 inhibitors
Effects of subcutaneous tirzepatide versus placebo or semaglutide on pancreatic islet function and insulin sensitivity in adults with type 2 diabetes: A multicentre, randomised, double-blind, parallel-arm, phase 1 clinical trial