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1 Introduction Besides the traditional standard-of-care agents, newer classes of glucose-lowering agents have been introduced and changed the landscape of type 2 diabetes mellitus (T2DM) management (1)
& Khoury, N
Without supplementation, deficiency is nearly universal within 23 years People taking metformin long-term metformin use reduces B12 absorption by 1030% through calcium-dependent ileal uptake disruption [4] People taking PPIs or H2 blockers acid suppression impairs B12 release from food proteins
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