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Weghuber compared the findings from STEP TEENS with those found in SCALE TEENS, a trial in which adolescents with obesity were randomly assigned to 3.0 mg of liraglutide (Saxenda, Novo Nordisk) or placebo

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Mou Y, Wang J, Wu J, He D, Zhang C, Duan C, et al

Similarly, T2D upregulates the expression of acetylcholinesterase (AChE), and suppresses that of antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH) while enhancing the expression of TNF, IL-1, IL-6, NF-B, and caspase-3 and production of malonaldehyde (MDA) and subsequent progression of CD