glp-1 muscle pain Glucagon-like peptide-1 receptor agonists in arthritis: current insights and future directions Muscle Loss with GLP-1 Medications:

Code Availability The reproducibility of the curation algorithm can be verified by executing the provided scripts on Code Ocean 25

f , Fold change (log 2 ) in indicated whole cell or ER metabolites from ER-tag HEK293T cells treated with thapsigargin compared to untreated

mtDNA, enriched in unmethylated CpG motifs, activates pattern recognition receptors (PRRs) including cGAS and TLR9, amplifying inflammatory responses (Newman and Shadel, 2023)

Importantly, a series of standardized toxicological assessments confirmed the safety of UA, showing favorable profiles in both human and animal models, with minimal side effects (7, 9)