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Eur J Pharmacol 2018;827:21526 113

Notably, this review synthesizes the molecular mechanisms through which exercise mitigates atherosclerosis, encompassing the regulation of exercise-induced factor expression, promotion of iWAT browning and BAT activation, elevation of blood lactate concentration to facilitate lactylation modification, and suppression of diverse cell death pathways

AOD 9604 preferential activity at the beta-3 receptor means it promotes fat breakdown without significantly affecting cardiovascular function or respiratory dynamics