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The new obesity drugs work, but it's a dilemma when people have to stop taking them GOING OFF OBESITY DRUGS Over the past few decades, Jonathan Meyers endured several cycles of gaining, shedding, then regaining weight after attempting Keto, high protein, low fat, and calorie-restrictive diets

A Mayo Clinic study offers a potential answer by identifying a distinct biological subtype of obesity that responds especially well to tirzepatide, a medication that mimics two naturally occurring hormones involved in appetite and blood sugar regulation, moving the field closer to precision medicine for obesity

For people with type 2 diabetes, this means their HbA1c levels may rise, potentially increasing the risk of both acute hyperglycaemia and long-term diabetic complications

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