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The liver is one of the largest organs in the body and performs a remarkable number of vital tasks for the body, such as: Acts as the primary filter for blood that comes from the digestive system Produces and secretes bile that is necessary for digestion Stores vitamins, minerals and provides energy in the form of glycogen and fat Removes toxins from the blood Metabolizes drugs Makes proteins that are involved in blood clotting and maintaining appropriate blood pressure Many people know that dogs with impaired liver function benefit from a supplement that supports liver health, but even healthy dogs can benefit from a liver supplement under certain circumstances

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Senescent Leydig Cell Elimination & Testosterone Restoration in Aged Mice (Aging / PMC, 2020) FOXO4-DRI Disrupts FOXO4-p53 in Senescent Leydig Cells and Improves Testicular Microenvironment A study published in Aging (and indexed on PMC) demonstrated that FOXO4 is specifically expressed in human Leydig cells, with nuclear translocation of FOXO4 in elderly men correlating with decreased testosterone synthesis