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Indoor cleanup and prevention reduce recurrence

Aging Albany NY 12:1686716886 Gu M, Cooper JM, Butler P, Walker AP, Mistry PK, Dooley JS et al (2000) Oxidative-phosphorylation defects in liver of patients with wilsons disease

Interestingly, core clock genes can affect circadian rhythmicity and composition of the gut microbiota, with studies in Bmal1 - (56) and Per1/2 -deficient mice (57) reporting abolishment of diurnal microbial oscillations and a shift toward a more proinflammatory gut microbiota profile

Candidates include athletes with severe or recurrent cramping, and individuals whose conditions impair adequate oral hydration