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Hydroquinone (HQ), another well-studied whitening agent, has been used clinically in leading cosmetic hyperpigmentation treatment 23 , however, it was also found to cause serious problems by generating reactive oxygen species leading to oxidative damage of lipids and permanent loss of melanocytes

Dosing frequency and duration vary widely, with cycles typically lasting one to four weeks, followed by breaks to assess effects

doi:10.5142/jgr.2011.35.2.226 Lyon MR, Cline JC, Totosy de Zepetnek J, Shan JJ, Pang P, Benishin C

I would be interested to see further research in this area. With acknowledged benefits for people with diabetes, having first been approved for use in 2005, GLP-1 drugs for weight loss may re-position overweight and obesity in a clearly medical context, with the potential of reducing the historical stigma associated with these conditions