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All the experiments were repeated 3 times and the values represent the mean of triplicates and these values are given in the Fig

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Also, SA-SMEDDS exhibited a delayed in vivo elimination, increased bioavailability (2.1-fold), and enhanced liver accumulation

TRPM4 is activated by increased intracellular ATP concentration and oxidative stress, but it is inhibited by intracellular ATP depletion (Nilius et al., 2004